The impact of high pressures on CPAP on physiological parameters has limited data. In this study, preterm neonates on CPAP 5 cmH2O were placed on incrementally higher pressures for a brief period at each level. Cardiac output was the primary outcome.

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No differences in cardiac output were noted on CPAP pressures ranging from 5 to 13 cmH2O. 

 

Link to publication: https://pubmed.ncbi.nlm.nih.gov/30859756/